Despoina Papachrysanthou

Partner, Head of Transformation & Operations

KPMG in Greece

Despoina Papachrysanthou has more than 18 years of international experience in designing, leading, and delivering complex operational and digital transformation initiatives. She has successfully led 120+ strategic projects in Greece and abroad across a wide range of industries and business functions, contributing meaningfully to improving organizational efficiency, agility, and sustainable growth.

With deep expertise in Lean Management, Agile methodologies, and business process optimization, she applies a holistic, end-to-end approach to business transformation—from strategic design through to full operational implementation. Her methodology is grounded in leveraging cutting-edge technologies and systematically using data-driven decision-making, with particular emphasis on AI, RPA, and Machine Learning solutions that accelerate productivity and strengthen operational maturity.

At the core of her philosophy is the belief that true transformation is not limited to cost-cutting initiatives. Instead, it focuses on creating meaningful profitability and sustained bottom-line improvement through targeted optimizations, process redesign, team empowerment, and the use of technology as a catalyst for business value.

In parallel, she places strong emphasis on change management, strengthening organizational agility, and mobilizing people at all levels of the organization. She leverages modern performance measurement frameworks—such as KPI Cascade Strategy Models—to ensure that strategy, objectives, and outcomes remain fully aligned and measurable.

With a deep understanding of the demands of today’s business environment, Despoina serves as a strategic partner to organizations pursuing real, sustainable, and high-impact transformation.

  • Law and Public Administration, National and Kapodistrian University of Athens

  • Master of Business Administration, Hellenic American University

  • Lean Management System Master Level (3rd Star), Cardiff University

  • Black Belt Lean Six Sigma, IASSC

  • Agile Scrum Master, Scrum.org

  • ARIS Business Architect/Designer

  • Diploma in Insurance Studies, EIAS