Navigating the future's uncertainty requires a keen understanding of the risks on the horizon. This report provides a comprehensive analysis of the geopolitical challenges and opportunities that businesses will face in 2024 and beyond. Drawing from a cross-sectoral perspective, this paper highlights three major trends likely to impact business operations: trade policy restrictions, operational excellence, and AI governance gaps. It serves as a crucial tool for leaders to future-proof their strategies, ensuring resilience and agility in a rapidly shifting global geopolitical landscape.